Original Antigenic Sin and the Folly of Our Universal Vaccination Campaign

M.H.V. Van Regenmortel, in Encyclopedia of Virology (Third Edition), 2008 Antigenicity or antigenic reactivity refers to the capacity of viruses to bind to specific antibody molecules. The antigenicity of nonenveloped viruses resides in the antigenic sites or B-cell epitopes of capsid proteins that are recognized by the binding sites of antibodies. Protein epitopes are classified as either continuousContinue reading “Original Antigenic Sin and the Folly of Our Universal Vaccination Campaign”